Categories

Publications

2023

Unal, M., Uppuganti, S., Dapaah, DY., Ahmed, R., Pennings J.,Willett, TL, Poziyon, P, & Nyman JS “Effect of ribose incubation on physical, chemical, and mechanical properties of human cortical bone.” Journal of the Mechanical Behavior of Biomedical Materials (2023) doi: 10.1016/j.jmbbm.2023.105731

Ahmed, R., Unal, M., Gautam, R., Uppuganti, S., Derasari, S., Mahadevan-Jansen, A., & Nyman, J. (2023). Sensitivity of Amide I band to matrix manipulation: a Raman micro-spectroscopy and Spatially Offset Raman Spectroscopy study. Analyst (2023) doi: 10.1039/D3AN00527E

Gautam, R., Ahmed, R., Haugen, E., Unal, M., Fitzgerald, S., Uppuganti, S., … & Nyman, J. S. Assessment of spatially offset Raman spectroscopy to detect differences in bone matrix quality. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2023), doi: 10.1016/j.saa.2023.123240

Ozturk, S., Cuneyit, I., Altuntas, F., Karagur ER., Cort-Donmez A., Ocak M., Unal M., Sarikanat M., Donmez BO., “Resveratrol prevents ovariectomy-induced bone quality deterioration by improving the microarchitectural and biophysicochemical properties of bone.” Journal of Bone and Mineral Metabolism (2023). https://doi.org/10.1007/s00774-023-01416-z

2022

Unal, M., Wilson, R. L., Neu, C. P., & Akkus, O. “Raman spectroscopy‐based water measurements identify the origin of MRI T2 signal in human articular cartilage zones and predict histopathologic score.” Journal of Biophotonics (2022) doi: 10.1002/jbio.202100212

2021

Unal, M., Ahmed, R., Mahadevan-Jansen, A., & Nyman, J.  “Compositional assessment of bone by Raman spectroscopy.” Analyst (2021), 146,  7464-7490 doi: 10.1039/D1AN01560E

Unal M., “Raman spectroscopic determination of bone matrix quantity and quality augments prediction of human cortical bone mechanical properties”, Journal of Biomechanics (2021), 119, 110342 doi: 10.1016/j.jbiomech.2021.110342.

2020

Unal M. “Letter to the Editor”.  Connective Tissue Research (2020), 61:5, 420-422, doi:10.1080/03008207.2019.1666113

Creecy A., Uppuganti S., Unal M., Voziyan P., Nyman JS., “The Age-Related Decrease in Material Properties of BALB/c Mouse Long Bones Involves Alterations to the Extracellular Matrix”.  Bone (2020), 130 (115126) doi:10.1016/j.bone.2019.11510

Fowlkes J., Bunn RC., Ray P., Kalaitzoglou E., Uppuganti S., Unal M., Nyman J., Thrailkill KM.,  “Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization” , Bone (2020) 130 (115106) doi: 10.1016/j.bone.2019.115126

Unal M. “Tasarımın Uzun Boyun Seramik Femoral Baş Protezinin Yüksek Kırılma Oranına Katkısının Sonlu Elemanlar Analizi ile Araştırılması” Akademik Platform Mühendislik ve Fen Bilimleri Dergisi (2020), 8(2), doi:10.21541/apjes.579931

2019

Unal M., Akkus, O., Sun, J., Cai, L., Erol, U. L., Sabri, L., and Neu, C. P. Raman spectroscopy-based water content is a negative predictor of articular human cartilage mechanical function. Osteoarthritis and Cartilage (2019) 27 (2), 304-313.doi: 0.1016/j.joca.2018.10.003

Unal M., Uppuganti S., Timur S., Akkus O.,  Nyman JS., “Assessing bone matrix quality by Raman spectroscopy helps predict fracture toughness of human cortical bone”. Scientific Reports (2019) 9(1)  7195 doi:10.1038/s41598-019-43542-7

Nyman JS., Uppuganti S., Unal M., Leverant CL., Adabala S., Mathilde, G., Voziyan P., Does M.D., “Manipulating the amount and structure of the organic matrix affects the water compartments of human cortical bone”. JBMR Plus (2019) doi.org: 10.1002/jbm4.10135

Unal M., “Bound Water and Hydroxyproline are the essential contributors to collagen molecular stability: A Computational Analysis”, Academic Platform Journal of Engineering and Science (2019), 7 (3), 373-3802

2018

Creecy A., Uppuganti S., Unal M., Bunn RC, Voziyan P., Nyman JS., “Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age”. Bone (2018); doi: 10.1016/j.bone.2018.02.005

Unal M., Uppuganti S., Leverant CL., Creecy A. Mathilde, G., Voziyan P., Nyman JS., ‘’Assessing Glycation-mediated Changes in Human Cortical Bone with Raman Spectroscopy.’’ Journal of Biophotonics (2018) doi: 10.1002/jbio.201700352

Unal M., Creecy A and Nyman JS, The Role of Matrix Composition in the Mechanical Behavior of Bone’’ Current Osteoporosis Reports (2018) doi:10.1007/s11914-018-0433-0

Unal M., Akkus O., “Shortwave-Infrared Raman Spectroscopic Classification of Water Fractions in Articular Cartilage ex vivo”. Journal of Biomedical Optics (2018); 23 (1), 015008. doi: 10.1117/1.JBO.23.1.015008

Unal M., Cingoz F., Bagcioglu C., Sozer Y. and Akkus O., “Interrelationship between electrical, mechanical and hydration properties of cortical bone”. Journal of the Mechanical Behavior of Biomedical Materials (2018); 77 (12-23). doi: 10.1016/j.jmbbm.2017.08.033

2017

Li B., Singer N., Rosenthal, N. Unal M., Haggins, D. Yeni, Y.N., Akkus O., “Chemical characterization of Maltese-cross birefringent crystals in synovial fluid samples collected from symptomatic joints” Joint Bone Spine (2017); 10.1016/j.jbspin.2017.09.004

Flanagan C. D., Unal M. , Akkus O. , Rimnac C. M.,” Raman spectral markers of human bone tissue are affected by radiation sterilization and high cycle fatigue damage” Journal of the Mechanical Behavior of Biomedical Materials (2017); 75 (314-321). doi:10.1016/j.jmbbm.2017.07.016

Jung H., Thomas M., Unal M., Akkus O., “Repetitive short-span application of extracellular calcium is osteoinductive to osteopregenitor cells.” Journal of Tissue Engineering and Regenerative Medicine (2017); 12(3), 1349-1359. doi: 10.1002/term.2518

Baumgaertel S., Jones Clark L., Unal M.,”Miniscrew Biomechanics: Guidelines for the Use of Indirect Anchorage Mechanics”. American Journal of Orthodontics and Dentofacial Orthopedics (2017); 152(3), 413-419. doi: 10.1016/j.ajodo.2017.04.020

2016

Unal M., Jung H., Akkus O., “Novel Spectroscopic biomarkers indicate that post-yield damage denatures bone’s collagen”. Journal of Bone and Mineral Research (2016); 31 (1015-1025). doi: 10.1002/jbmr.2768

Donmez B. O., Unal M., Ozdemir S. ,Ozturk N., Oguz N., Akkus O., “Effects of Losartan treatment on physicochemical properties of diabetic rat bone”. Journal of Bone and Mineral Metabolism (2016); 35(2),161-170. doi: 10.1007/s00774-016-0748-9

2015

Unal M., Akkus O., “Raman Spectral Classification of Mineral- And Collagen-Bound Water’s Associations to Elastic and Post-Yield Mechanical Properties of Cortical Bone”. Bone (2015); 81 (315- 326). doi:10.1016/j.bone.2015.07.024;

2014

Unal M., Yang S., Akkus O., “Molecular Spectroscopic Identification of the Water Compartments in Bone”. Bone (2014); 67(228-236). doi: 10.1016/j.bone.2014.07.021

Unal M.#, Alapan Y.#, Jia H., Varga G. A., Angelino K., Aslan M., Sayin I., Han C., Jiang Y., Zhang Z., Gurkan U. A., “Micro and Nanoscale Technologies for Cell Mechanics”. Nanobiomedicine (2014); 1:5. doi: 10.5772/59379, #equally contributed